Mental Health World Conference 2026

Abstract

In clinical practice, many patients with non communicable major diseases (e.g., cancer, chronic inflammation) often experience a sudden physical and mental collapse after medical check up. Individuals with normal sleep, personality, work and living conditions may suffer an instant mental breakdown upon being diagnosed with suspected severe diseases via physical examination. Severe depression, anxiety and somatic symptoms emerge in a short period, leading to rapid deterioration of the condition. This phenomenon profoundly reveals the close correlation between mental emotion and physical health, namely, psychology determines physiology. This paper aims to explore how psychological stress (depression, fear) destroys the bodys immune system and aggravates somatic lesions by inducing aseptic neuroinflammation in the brain. On this basis, the core diagnostic and therapeutic principle of  treating the spirit first, and antidepressant first, is proposed to cure diseases, advocating the reshaping of immune homeostasis by relieving ideological burden, relaxing the body and mind, and eliminating stress. Meanwhile, it demonstrates that Tagetes erecta extract, as a core substance for anti-aseptic inflammation and antidepressant therapy, plays a key role in the bidirectional regulation of "psychology physiology, so as to provide a brand-new theoretical basis and practical approach for the comprehensive prevention and treatment of major diseases.